Factory High Purity Ciclopirox CAS 29342

• Overview
• Product Description
• Product Details
• Application&Function
• Specification

Overview

Basic Info.

Model NO.	XMHT Ciclopirox
Certification	GMP, HSE, ISO 9001, USP, BP
Suitable for	Elderly, Children, Adult
State	Powder
Purity	>99%
Product Name	Ciclopirox
Appearance	White to off-White Crystalline Powder
Grade	Pharmaceutical Grade
CAS No.	29342-05-0
Mf	C12h17no2
MW	207.26900
Density	1.193 g/cm3
Melting Point	1440c
Boiling Point	350ºC at 760 Mmhg
Refractive Index	1.582
Assay	>99%
Application	Pharmaceutical
Specific	COA
Test Method	HPLC
Shelf Life	2 Years
Transport Package	Negotiable
Specification	>99%
Trademark	XMHT
Origin	Xian
Production Capacity	4000kg/Month

Product Description

Factory High Purity Ciclopirox CAS 29342-05-0 Antifungal CiclopiroxProduct Description

Product Details

Product Name	Ciclopirox
Appearance	White Powder
CAS	29342-05-0
MF	C12H17NO2
MW	207.26888

Ciclopirox is a synthetic antifungal agent with the chemical name 6cyclohexyl1hydroxy4methyl2(1H)pyridone It appears as a white to almost white crystalline powder Practically insoluble in water but soluble in organic solvents such as ethanol and dimethylformamide It has a characteristic infrared spectrum and its identity is confirmed by comparison with a reference standard The assay is performed by HPLC with a purity requirement of not less than 990 percent Related substances are controlled with individual impurities not exceeding 03 percent Loss on drying is typically not more than 05 percent Residue on ignition is limited to not more than 01 percent Heavy metals are controlled to not more than 20 ppm Microbial limits and specific tests ensure its suitability for pharmaceutical useApplication&Function

Ciclopirox is a broadspectrum antifungal agent with additional antibacterial and antiinflammatory properties It works primarily by chelating polyvalent metal cations such as which are essential cofactors for enzymes involved in cellular processes This chelation disrupts vital fungal functions including mitochondrial electron transport and energy production leading to fungal cell death Unlike many antifungals Ciclopirox does not target ergosterol synthesis making it effective against strains resistant to other antifungals Its mechanism extends to inhibiting biofilm formation which is crucial for treating nail and skin infections where biofilms often protect the pathogens Ciclopirox also exhibits antiinflammatory effects by modulating the activity of immune cells and reducing the production of inflammatory cytokines which helps alleviate symptoms like redness and itching associated with infections Its penetration into the nail plate and stratum corneum is excellent making it a firstline topical treatment for onychomycosis fungal nail infections tinea pedis athletes foot tinea corporis ringworm and cutaneous candidiasis For onychomycosis it is formulated as a nail lacquer which forms a protective film allowing sustained drug release and deep penetration into the infected nail This topical application minimizes systemic side effects Commonly it is applied once daily to affected areas Treatment duration varies but typically lasts several weeks to months until clinical cure is achieved It is also found in shampoos for treating seborrheic dermatitis and dandruff where its antifungal action against Malassezia yeast and its antiinflammatory effects provide dual therapeutic benefit Its efficacy safety profile and lack of systemic absorption make it a valuable option in dermatologySpecification